PeproTech大鼠抗小鼠CD25 SAFIRE (Functional)
产品名称: PeproTech大鼠抗小鼠CD25 SAFIRE (Functional)
英文名称: Anti-Mouse CD25 SAFIRE Purified
产品编号: 07312-25-500
产品价格: null
产品产地: USA
品牌商标: peperotech(BioGems)
更新时间: null
使用范围: 功能性,流式
美国PeproTech(派普泰克)公司中国代表处
- 联系人 :
- 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
- 邮编 : 215123
- 所在区域 : 江苏
- 电话 : 点击查看
- 传真 : 点击查看
- 邮箱 : peprotech.infochina@thermofisher.com
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation. The PC61.5 antibody blocks the binding of IL-2 to both high-affinity and low-affinity receptors.