PTK2 polyclonal antibody
产品名称： PTK2 polyclonal antibody
英文名称： PTK2 polyclonal antibody
产品编号： PAB18153
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTK2.
- Immunogen:
- A synthetic peptide corresponding to human PTK2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to PTK2.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.
Chang F, Lemmon CA, Park D, Romer LH.Mol Biol Cell. 2007 Jan;18(1):253-64. Epub 2006 Nov 8.
- 2.
- FAK-dependent regulation of myofibroblast differentiation.
Greenberg RS, Bernstein AM, Benezra M, Gelman IH, Taliana L, Masur SK.FASEB J. 2006 May;20(7):1006-8. Epub 2006 Apr 3.
- 3.
- Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake.
Bruce-Staskal PJ, Weidow CL, Gibson JJ, Bouton AH.J Cell Sci. 2002 Jul 1;115(Pt 13):2689-700.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from NIH/3T3 cells, using PTK2 polyclonal antibody (Cat # PAB18153).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 5747
- Protein Accession#:
- Q05397
- Gene Name:
- PTK2
- Gene Alias:
- FADK,FAK,FAK1,pp125FAK
- Gene Description:
- PTK2 protein tyrosine kinase 2
- Omim ID:
- 600758
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq
- Other Designations:
- focal adhesion kinase 1
- Interactome
