FEM1A,前列腺素E受体4相关蛋白抗体

产品编号HZ-6861R
英文名称FEM1A
中文名称前列腺素E受体4相关蛋白抗体
别 名EPRAP; Fem-1 homolog a (C. elegans); Fem1 homolog a; FEM1-alpha-A; FEM1a-A; Fem1aa; Feminization 1 homolog a (C. elegans); Feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; Protein fem-1 homolog A-A; FEM1A_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
FEM1A,前列腺素E受体4相关蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FEM1A
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FEM1A,前列腺素E受体4相关蛋白抗体PubMedPubMed
产品介绍background:
FEM1A is a caspase substrate homologous to the C. Elegans sex determining protein, FEM-1. Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Overexpression of FEM1A in mammalian cells is reported to induce apoptosis.

Function:
Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4.

Subunit:
Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4.

Subcellular Location:
Cytoplasm (Probable).

Tissue Specificity:
Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).

FEM1A,前列腺素E受体4相关蛋白抗体Similarity:
Belongs to the fem-1 family.
Contains 9 ANK repeats.
Contains 2 TPR repeats.

Gene ID:
55527

Database links:
Entrez Gene: 516550 Cow
Entrez Gene: 55527 Human
Entrez Gene: 14154 Mouse
Entrez Gene: 316131 Rat
GenBank: NP_061178.1 Human
SwissProt: Q29RM5 Cow
SwissProt: Q9BSK4 Human
SwissProt: Q8C4V3 Mouse
SwissProt: Q4V890 Rat
Unigene: 515082 Human
Unigene: 290813 Mouse
Unigene: 228392 Rat
Unigene: 97265 Rat

FEM1A,前列腺素E受体4相关蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.