GYPA monoclonal antibody, clone HIR2
产品名称： GYPA monoclonal antibody, clone HIR2
英文名称： GYPA monoclonal antibody, clone HIR2
产品编号： MAB3852
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of GYPA.
- Immunogen:
- A synthetic peptide corresponding to N-terminus of human GYPA.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes N-terminal portion of glycophorin A (and weakly ofglycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K-562 and HEL, but not on all other cells.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry: This HIR2 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes and cell agglutination assay and can be used at approximately 0.1 mg per million cells.
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hsa, an adhesin of Streptococcus gordonii DL1, binds to alpha2-3-linked sialic acid on glycophorin A of the erythrocyte membrane.
Yajima A, Urano-Tashiro Y, Shimazu K, Takashima E, Takahashi Y, Konishi K.Microbiol Immunol. 2008 Feb;52(2):69-77.
- 2.
- Flow cytometric analysis of human bone marrow perfusion cultures: erythroid development and relationship with burst-forming units-erythroid.
Rogers CE, Bradley MS, Palsson BO, Koller MR.Exp Hematol. 1996 Apr;24(5):597-604.
- 3.
- Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers.
Nakahata T, Okumura N.Leuk Lymphoma. 1994 May;13(5-6):401-9. Review.
- Application Image
- Immunohistochemistry (Frozen sections)
- Agglutination
- Flow Cytometry
- Entrez GeneID:
- 2993
- Gene Name:
- GYPA
- Gene Alias:
- CD235a,GPA,GPErik,GPSAT,GpMiIII,HGpMiIII,HGpMiV,HGpMiX,HGpMiXI,HGpSta(C),MN,MNS
- Gene Description:
- glycophorin A (MNS blood group)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
- Other Designations:
- Mi.V glycoprotein (24 AA),erythroid-lineage-specific membrane sialoglycoprotein,glycophorin A,glycophorin A (MN blood group),glycophorin A MNS blood group,glycophorin A, GPA,glycophorin Erik,glycophorin MiI,glycophorin MiIII,glycophorin MiV,glycophorin Mi
- Gene Pathway