Cux2,转录同源蛋白质CUX2抗体

产品编号HZ-11832R
英文名称Cux2
中文名称转录同源蛋白质CUX2抗体
别 名CDP2; Cut like homeobox 2; Cut-like 2; CUTL2; CUX2; Homeobox protein cut-like 2; Homeobox protein cux 2; Homeobox protein Cux-2; KIAA0293; CUX2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域神经生物学 信号转导 干细胞 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
Cux2,转录同源蛋白质CUX2抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量162kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Cux2 (1001-1085aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cux2,转录同源蛋白质CUX2抗体PubMedPubMed
产品介绍background:
Cux2 is a marker for cortical subpopulations. Cux2 is an orthologue of the Drosophila cut gene, which encodes a homeodomain protein involved in neuronal specification. During cortical development Cux2 identifies two subpopulations with different spatial origins, migratory behaviours and phenotypic characteristics: (i) a population of interneurons, which invades the pallium from the subpallium; and (ii) a neuronal population produced in the pallium around embryonic day 11.5, which divides in the SVZ and accumulates in the intermediate zone (IZ). Subsequently, Cux2 is a marker of upper cortical layers.

Function:
May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner

Subcellular Location:
Nuclear

DISEASE:

Similarity:
Belongs to the CUT homeobox family.
Contains 3 CUT DNA-binding domains.
Contains 1 homeobox DNA-binding domain.

Gene ID:
23316

Cux2,转录同源蛋白质CUX2抗体Database links:
Entrez Gene: 23316 Human
Entrez Gene: 13048 Mouse
Entrez Gene: 288665 Rat
Omim: 610648 Human
SwissProt: O14529 Human
SwissProt: P70298 Mouse
Unigene: 124953 Human
Unigene: 156172 Mouse
Unigene: 332661 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-Cux2 Polyclonal Antibody, Unconjugated(HZ-11832R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-Cux2 Polyclonal Antibody, Unconjugated(HZ-11832R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining