FITC标记的DPY19L2蛋白抗体
产品名称： FITC标记的DPY19L2蛋白抗体
英文名称： Anti-DPY19L2/FITC
产品编号： HZ-8291R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-DPY19L2/FITC Conjugated antibody
FITC标记的DPY19L2蛋白抗体
| 产品编号 | bs-8291R-FITC |
| 英文名称 | Anti-DPY19L2/FITC |
| 中文名称 | FITC标记的DPY19L2蛋白抗体 |
| 别 名 | D19L2_HUMAN; dpy 19 like 2; dpy 19 like 2 (C. elegans); Dpy 19 like protein 2; Dpy-19-like protein 2; dpy19; DPY19L2; FLJ32949; FLJ36166; Protein dpy 19 homolog 2; Protein dpy-19 homolog 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 87kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DPY19L2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Required during spermatogenesis for sperm head elongation and acrosome formation. Function: Required during spermatogenesis for sperm head elongation and acrosome formation. Subunit: Membrane; Multi-pass membrane protein (Potential). Subcellular Location: Involvement in disease：Defects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) . An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS. Tissue Specificity: Widely expressed with high expression in testis. DISEASE: Defects in DPY19L2 are the cause of spermatogenic failure type 9 (SPGF9) [MIM:613958]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of SPGF9. Similarity: Belongs to the dpy-19 family. Database links: UniProtKB/Swiss-Prot: Q6NUT2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicatio |
参与疾病：DPY19L2中的缺陷是GooBooSoviMess（GiguloOS）的一个原因。精子发生缺陷引起的不孕症。最突出的特征是顶体畸形。在最严重的情况下顶体完全缺失。球形精子症的特点是细胞核形状异常，精子线粒体排列异常。注意：DPY19L2中的删除可能是GuangZoOS的主要原因。