DEFB124,防御素β-124/β-defensin 124抗体

产品编号HZ-14252R
英文名称DEFB124
中文名称防御素β-124/β-defensin 124抗体
别 名Beta defensin 24; Beta-defensin 124; DEFB 24; DB124_HUMAN; DEFB24; Defensin, beta 124.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 发育生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
DEFB124,防御素β-124/β-defensin 124抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量5.2kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DEFB124
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DEFB124,防御素β-124/β-defensin 124抗体PubMedPubMed
产品介绍background:
Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 124 is a 71 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

Function:
DEFB124 has antibacterial activity.

Subcellular Location:
Secreted

Similarity:
Belongs to the beta-defensin family.

Gene ID:
245934

DEFB124,防御素β-124/β-defensin 124抗体Database links:
Entrez Gene: 245934 Human
SwissProt: Q8NES8 Human
Unigene: 381373 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.