NBN monoclonal antibody (M02), clone 2C7
产品名称: NBN monoclonal antibody (M02), clone 2C7
英文名称: NBN monoclonal antibody (M02), clone 2C7
产品编号: H00004683-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant NBN.
- Immunogen:
- NBN (NP_002476, 645 a.a. ~ 754 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DDSEMLPKKLLLTEFRSLVIKNSTSRNPSGINDDYGQLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged NBN is 0.3 ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 4683
- GeneBank Accession#:
- NM_002485
- Protein Accession#:
- NP_002476
- Gene Name:
- NBN
- Gene Alias:
- AT-V1,AT-V2,ATV,FLJ10155,MGC87362,NBS,NBS1,P95
- Gene Description:
- nibrin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq
- Other Designations:
- Nijmegen breakage syndrome 1 (nibrin),cell cycle regulatory protein p95,p95 protein of the MRE11/RAD50 complex
- Gene Pathway
- Related Disease
- Acute Disease
- Adenocarcinoma
- Astrocytoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Basal Cell
- Carcinoma, Ductal
- Carcinoma, Ductal, Breast
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Transitional Cell
- Central Nervous System Neoplasms
- Chromosomal Instability
- Chromosome Aberrations
- Chromosome Breakage
- Chromosome Deletion
- Cleft Lip
- Cleft Palate