FITC标记的磷酸化膜突蛋白抗体
产品名称： FITC标记的磷酸化膜突蛋白抗体
英文名称： Anti-phospho-Moesin (Thr558)/FITC
产品编号： HZ-17703R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-phospho-Moesin (Thr558)/FITC Conjugated antibody
FITC标记的磷酸化膜突蛋白抗体
| 英文名称 | Anti-phospho-Moesin (Thr558)/FITC |
| 中文名称 | FITC标记的磷酸化膜突蛋白抗体 |
| 别 名 | Moesin (phospho T558); p-Moesin (phospho T558); Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin; Moesin/anaplastic lymphoma kinase fusion protein; MSN; MSN/ALK fusion. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 68kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human Moesin around the phosphorylation site of Thr558 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008] Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. Subcellular Location: Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. Tissue Specificity: In all tissues and cultured cells studied. Post-translational modifications: Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures. Similarity: Contains 1 FERM domain. Database links: Entrez Gene: 4478 Human Entrez Gene: 17698 Mouse Omim: 309845 Human SwissProt: P26038 Human SwissProt: P26041 Mouse Unigene: 87752 Human Unigene: 138876 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Moesin（膜组织延伸棘蛋白）是ErM家族的成员，包括Ezrin和Rexin。ERM蛋白似乎作为质膜和肌动蛋白基细胞骨架之间的交联剂发挥作用。Moesin局限于丝状突起和其他膜状突起，这些突起对细胞识别和信号传导以及细胞运动很重要。[ RefSeq，JUL 2008 ]