CARD17,凋亡加强结构域蛋白17/INCA抗体

产品编号HZ-7090R
英文名称CARD17
中文名称凋亡加强结构域蛋白17/INCA抗体
别 名CAR17_HUMAN; CARD 17; CARD17; Caspase 1 inhibitor; Caspase recruitment domain containing protein 17; Caspase recruitment domain-containing protein 17; Caspase-1 inhibitor INCA; Caspase1 inhibitor; Inhibitory caspase recruitment domain (CARD) protein; Inhibitory caspase recruitment domain protein.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
CARD17,凋亡加强结构域蛋白17/INCA抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from humna CARD17/INCA
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CARD17,凋亡加强结构域蛋白17/INCA抗体PubMedPubMed
产品介绍background:
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Function:
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Subunit:
Interacts with pro-CASP1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 CARD domain.

CARD17,凋亡加强结构域蛋白17/INCA抗体Database links:
UniProtKB/Swiss-Prot: Q5XLA6.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.