Active人ARMET全长蛋白质-蛋白质/抗原/多肽-试剂-生物在线
深圳市宇德立生物科技有限公司
Active人ARMET全长蛋白质

Active人ARMET全长蛋白质

商家询价

产品名称： Active人ARMET全长蛋白质

英文名称： Arginine rich mutated in early stage tumors Arginine rich protein Arginine-rich protein ARMET ARMET protein ARP Manf MANF_HUMAN Mesencephali

产品编号： ab206464

产品价格： 0

产品产地： 英国

品牌商标： abcam

更新时间： null

使用范围： null

深圳市宇德立生物科技有限公司
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  • 地址 : 深圳市宝安区西乡宝民二路贤基大厦4E
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  • 所在区域 : 广东
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进入展台

 

  • 性质Recombinant
  • 来源CHO
  • 氨基酸序列
    • AccessionP55145
    • 种属Human
    • 序列LRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRL CYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQ IDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPK AASARTDL
    • 分子量18 kDa
    • 氨基酸25 to 182
    • 额外的序列信息This product is for the mature full length protein. The signal peptide is not included.

技术指标

Our Abpromise guarantee covers the use of ab206464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Protein is biologically active. Suitable for cell culture and in vivo testing. Human recombinant ARMETL1 has been tested in rat 6-OHDA model of Parkinsons disease and shown neureprotection and neurorestoration. ARMETL1 has also shown neuroprotection in animal models of stroke.

  • 应用

    SDS-PAGE

    Functional Studies

    Mass Spectrometry

  • 内毒素水平< 1.000 Eu/mg
  • 形式Liquid
  • 浓度10 µg 浓度为 1 mg/ml 

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Arginine rich mutated in early stage tumors
    • Arginine rich protein
    • Arginine-rich protein
    see all
  • 功能Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • 序列相似性Belongs to the ARMET family.
  • 结构域The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • 翻译后修饰May contain sialic acid residues.
  • 细胞定位Secreted.
  • Information by UniProt

Active human ARMET full length protein 图像

  • Western blot - Active human ARMET full length protein (ab206464)
    Western blot - Active human ARMET full length protein (ab206464)
    anti-ARMET polyclonal antibody + ab206464 expressed into the supernatant of CHO cell culture medium
  • SDS-PAGE - Active human ARMET full length protein (ab206464)
    SDS-PAGE - Active human ARMET full length protein (ab206464)