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上海信裕生物科技有限公司
MFN1抗体

MFN1抗体

商家询价

产品名称： MFN1抗体

英文名称： MFN1Antibody

产品编号： XY13798-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 MFN1抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications WB Publications 4 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 13798-1-AP;human kidney tissuehuman kidney tissue were subjected to SDS PAGE followed by western blot with 13798-1-AP(MFN1 antibody) at dilution of 1:500
  • 13798-1-AP;human lung cancerImmunohistochemical of paraffin-embedded human lung cancer using 13798-1-AP(MFN1 antibody) at dilution of 1:100 (under 10x lens)
  • 13798-1-AP;human lung cancerImmunohistochemical of paraffin-embedded human lung cancer using 13798-1-AP(MFN1 antibody) at dilution of 1:100 (under 40x lens)
Positive WB detected in Human kidney tissue
Positive IHC detected in Human lung cancer tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 MFN1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information MFN1抗体
Immunogen MFN1 fusion protein ag4762 Full name Mitofusin 1
Calculated molecular
weight		 741aa,84 kDa Observed molecular 
weight		 86kd
GenBank accession 
number		 BC040557 Gene ID (NCBI) 55669
Gene symbol MFN1 Synonyms DKFZp762F247, FLJ20693, Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
Background

Mitofusin-1 (MFN1) is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). Mitofusins are large predicted GTPases located in outer mitochondrial membrane. They are essential for outer membrane fusion by interacting with each other to facilitate mitochondrial targeting. The mitofusins are the first known protein mediator of mitochondrial fusion, and mediate developmentally regulated post-meiotic fusion of mitochondria.Mfn1 is required on adjacent mitochondria to mediate fusion via interactions of a heptad repeat region that mediates oligomerization of the protein(PMID:16892085). MFN1抗体

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