FBXL20,FBXL20蛋白抗体

产品编号HZ-8473R
英文名称FBXL20
中文名称FBXL20蛋白抗体
别 名F box/LRR repeat protein 20; F box/LRR repeat protein 2 like; F box/LRR repeat protein 20; Fbl2; Fbl20; F box and leucine rich repeat protein 20; MGC15482; SCR; SCRAPPER; FXL20_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,
FBXL20,FBXL20蛋白抗体产品应用WB=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FBXL20
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FBXL20,FBXL20蛋白抗体PubMedPubMed
产品介绍background:
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.

Subunit:
Interacts with SKP1 and CUL1.

Subcellular Location:
Cytoplasmic.

FBXL20,FBXL20蛋白抗体Similarity:
Contains 1 F-box domain.
Contains 13 LRR (leucine-rich) repeats.

Gene ID:
84961

Database links:
Entrez Gene: 84961 Human
Entrez Gene: 72194 Mouse
Entrez Gene: 64039 Rat
SwissProt: Q96IG2 Human
SwissProt: Q9CZV8 Mouse
SwissProt: Q9QZH7 Rat

FBXL20,FBXL20蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片	Protein: mouse kidney;  Primary: Anti-FBXL20 (HZ-8473R) at 1:600;  Secondary: HRP conjugated Goat-Anti-rabbit IgG(HZ-0295G-HRP) at 1: 5000;  Predicted band size:48kD Observed band size:48 kD