FITC标记的视黄醇结合蛋白4抗体
产品名称： FITC标记的视黄醇结合蛋白4抗体
英文名称： Anti-RBP4/FITC
产品编号： HZ-6182R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RBP4/FITC Conjugated antibody
FITC标记的视黄醇结合蛋白4抗体
| 英文名称 | Anti-RBP4/FITC |
| 中文名称 | FITC标记的视黄醇结合蛋白4抗体 |
| 别 名 | plasma retinol binding protein 4; Plasma retinol-binding proteinv; Plasma retinol-binding protein(1-176); prbp; PRO2222; RBP; RBP4; RET4_HUMAN; Retinol binding protein 4; retinol binding protein 4 interstitial; Retinol binding protein 4 plasma. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 免疫学 糖尿病 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBP4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]. Function: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. Subcellular Location: Secreted. DISEASE: Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. Similarity: Belongs to the calycin superfamily. Lipocalin family. Database links: Entrez Gene: 5950 Human Omim: 180250 Human SwissProt: P02753 Human Unigene: 50223 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该蛋白属于脂蛋白家族，是血液中维生素A（维生素A醇）的特异载体。它将视黄醇从肝脏储存到周围组织。在血浆中，RBP视黄醇复合物与甲状旁腺素相互作用，通过肾小球滤过防止其损失。维生素A的缺乏阻碍翻译后结合蛋白的分泌，导致有缺陷的递送和供应到表皮细胞。[ RefSeq，JUL 2008 ]提供。