FITC标记的SKIP蛋白抗体
产品名称： FITC标记的SKIP蛋白抗体
英文名称： Anti-SKIP/FITC
产品编号： HZ-17506R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SKIP/FITC Conjugated antibody
FITC标记的SKIP蛋白抗体
| 英文名称 | Anti-SKIP/FITC |
| 中文名称 | FITC标记的SKIP蛋白抗体 |
| 别 名 | 43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SKIP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] Function: Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton. Subcellular Location: Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles. Tissue Specificity: Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. Similarity: Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family. Database links: Entrez Gene: 51763 Human Entrez Gene: 19062 Mouse Entrez Gene: 287533 Rat Omim: 607875 Human SwissProt: Q9BT40 Human SwissProt: Q8C5L6 Mouse Unigene: 632238 Human Unigene: 1458 Mouse Unigene: 7440 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一种蛋白，对聚磷酸肌醇具有5-磷酸酶活性。该蛋白定位在缺乏肌动蛋白应力纤维的区域中的细胞质中。据认为，这种蛋白质可能负调控肌动蛋白细胞骨架。另一种编码不同的异构体的剪接转录变体已被鉴定。[ RefSeq，OCT 2008提供]