内毒素:

Less than 1.0 EU per μg by the LAL method.



纯度:

>90% as determined by SDS-PAGE.



活性:

Measured by its binding ability in a functional ELISA. Immobilized Human HVEM, Strep Tag (Catalog # HVM-H5283) at 10μg/mL (100 μL/well) can bind Human CD160, His Tag (Catalog # BY5-H5229) with a linear range of 0.2-1.3 μg/mL.



产品背景:

CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.



产品描述:

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 33.2 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
SDS-PAGE


Human CD160, His Tag on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.