ANKS6,锚蛋白重复及SAM结构域蛋白6抗体

产品编号HZ-9099R
英文名称ANKS6
中文名称锚蛋白重复及SAM结构域蛋白6抗体
别 名ANKRD14; Anks6; ANKS6_HUMAN; ankyrin repeat and SAM domain containing protein 6; Ankyrin repeat and SAM domain-containing protein 6; ankyrin repeat domain 14; ankyrin repeat domain containing protein 14; Ankyrin repeat domain-containing protein 14; SAM domain containing protein 6; SAM domain-containing protein 6; SamCystin; SAMD6; sterile alpha motif domain containing 6; sterile alpha motif domain containing protein 6; Sterile alpha motif domain-containing protein 6.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
ANKS6,锚蛋白重复及SAM结构域蛋白6抗体克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量92kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ANKS6
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ANKS6,锚蛋白重复及SAM结构域蛋白6抗体PubMedPubMed
产品介绍background:
ANKS6, also known as ankyrin repeat domain-containing protein 14, SAMD6 (sterile alpha motif domain-containing protein 6), SamCystin or PKDR1, is an 871 amino acid phosphoprotein that contains eleven ANK repeats, one SAM domain and exists as three alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 9q22.33, ANKS6 is necessary for renal function and is linked to renal cyst formation in polycystic kidney disease. ANKS6 interacts with BICC1, another protein linked to polycystic kidney disease, and both co-localize to the same cell region. ANKS6 is involved in protein–protein interactions with both itself as well as BICC1, and both proteins function in a molecular pathway that is linked to cystogenesis. ANKS6 may also be associated with dental anomolies.

Function:
Required for renal function (By similarity).

Post-translational modifications:

DISEASE:

Similarity:
Contains 11 ANK repeats.
Contains 1 SAM (sterile alpha motif) domain.

ANKS6,锚蛋白重复及SAM结构域蛋白6抗体Database links:
UniProtKB/Swiss-Prot: Q68DC2.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.