Rap1-GTP 小鼠单抗
产品名称： Rap1-GTP 小鼠单抗
英文名称： Anti-Rap1-GTP Monoclonal Antibody
产品编号： 26912
产品价格： null
产品产地： 美国
品牌商标： Neweast Biosciences
更新时间： null
使用范围： IP, IHC, IF
武汉费斯德生物科技有限公司
- 联系人 :
- 地址 : 武汉东湖新技术开发区高新大道666号武汉国家生物产业基地项目（生物创新园）B.C.D区研发楼B3-3栋3楼
- 邮编 :
- 所在区域 : 湖北
- 电话 : 181****2833 点击查看
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- 邮箱 : nebio0923@163.com
| 货号: 26912 |
| 规格: 30 µL |
| 基因符号: RAP1 |
| 描述: Anti-Rap1-GTP Mouse Monoclonal Antibody |
| 背景介绍: Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K effectors of the MEK/ERK MAP-kinase pathway, Raf-1 and B-Raf. Rap1 regulates cell adhesion mechanisms through effector molecules such as the integrins and cadherins. |
| 免疫原: Recombinant full length protein of active Rap1. |
| 经过测试的应用: IP, IHC, IF |
| 推荐稀释比: IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Anti-Rap1-GTP monoclonal antibody recognizes active Rap1 of vertebrates. |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
免疫沉淀/蛋白质印迹:  Rap1 Activation Assay.Purified Rap1 proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-Rap1-GTP monoclonal antibody (Cat. No. 26912). Immunoblot was with an anti-Rap1 polyclonal antibody (Cat. No. 21104). |