SH3MD2 monoclonal antibody (M01), clone 3H3
产品名称： SH3MD2 monoclonal antibody (M01), clone 3H3
英文名称： SH3MD2 monoclonal antibody (M01), clone 3H3
产品编号： H00057630-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SH3MD2.
- Immunogen:
- SH3MD2 (NP_065921, 790 a.a. ~ 888 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
- Host:
- Mouse
- Reactivity:
- Human, Rat
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Sh3rf2/POSHER promotes cell survival by RING-mediated proteasomal degradation of the JNK scaffold POSH.
Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.J Biol Chem. 2011 Nov 28.
- Applications
- Western Blot (Cell lysate)
- SH3MD2 monoclonal antibody (M01), clone 3H3 Western Blot analysis of SH3MD2 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- SH3MD2 monoclonal antibody (M01), clone 3H3. Western Blot analysis of SH3MD2 expression in PC-12 ( Cat # L012V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged SH3MD2 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 57630
- GeneBank Accession#:
- NM_020870
- Protein Accession#:
- NP_065921
- Gene Name:
- SH3RF1
- Gene Alias:
- FLJ21602,KIAA1494,POSH,RNF142,SH3MD2
- Gene Description:
- SH3 domain containing ring finger 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq
- Other Designations:
- SH3 multiple domains 2,plenty of SH3 domains,plenty of SH3s,ring finger protein 142
- Related Disease