Anti-NRXN3 Polyclonal Antibody
产品名称: Anti-NRXN3 Polyclonal Antibody
英文名称: C14orf60
产品编号: K001914P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IHC
北京索莱宝科技有限公司--实验室产品
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This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.