CD8A monoclonal antibody, clone UCHT4
产品名称： CD8A monoclonal antibody, clone UCHT4
英文名称： CD8A monoclonal antibody, clone UCHT4
产品编号： MAB6898
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD8A.
- Immunogen:
- Native purified CD8A from human thymocytes/Sezary T cells.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I.
Sun J, Leahy DJ, Kavathas PB.J Exp Med. 1995 Nov 1;182(5):1275-80.
- 2.
- The CD8 coreceptor revisited: one chain good, two chains better.
Zamoyska R.Immunity. 1994 Jul;1(4):243-6.
- 3.
- Induction of a T-cell mediated suppressor activity by soluble products from antigen-specific helper/inducer human T-cell lines.
Fischer A, Beverley P, Feldmann M, Smith S.Immunology. 1983 Jan;48(1):177-86.
- Application Image
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 925
- Gene Name:
- CD8A
- Gene Alias:
- CD8,Leu2,MAL,p32
- Gene Description:
- CD8a molecule
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD8 antigen alpha polypeptide,CD8 antigen, alpha polypeptide (p32),Leu2 T-lymphocyte antigen,OKT8 T-cell antigen,T cell co-receptor,T-cell antigen Leu2,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,T8 T-cell ant