CPB2 Pre-design Chimera RNAi
产品名称： CPB2 Pre-design Chimera RNAi
英文名称： CPB2 Pre-design Chimera RNAi
产品编号： H00001361-R02
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens carboxypeptidase B2 (plasma, carboxypeptidase U) (CPB2), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_016413
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 1361
- Gene Name:
- CPB2
- Gene Alias:
- CPU,PCPB,TAFI
- Gene Description:
- carboxypeptidase B2 (plasma)
- Omim ID:
- 603101
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018364,OTTHUMP00000018365,bA139H14.2 (carboxypeptidase B2 (plasma)),carboxypeptidase B-like protein,carboxypeptidase B2 (plasma, carboxypeptidase U),carboxypeptidase U,plasma carboxypeptidase B2,thrombin-activable fibrinolysis inhibitor,thromb
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Aneurysm, Ruptured
- Angina Pectoris
- Antiphospholipid Syndrome
- Behcet Syndrome
- Brain Ischemia
- Cadaver
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cerebral Infarction
- Coronary Artery Disease
- Coronary Disease
- Death, Sudden, Cardiac
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hemorrhage
- Hemorrhagic Disorders