Anti-MAP3K10抗体
产品名称： Anti-MAP3K10抗体
英文名称： MAP3K10
产品编号： YB--6781R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
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Anti-MAP3K10抗体
| 产品编号 | YB-6781R |
| 英文名称 | MAP3K10 |
| 中文名称 | 丝裂原活化蛋白激酶3K10抗体 |
| 别 名 | Activates the JUN N-terminal pathway; M3K10_HUMAN. |
| 规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 信号转导 细胞凋亡 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Xenopuslaevis |
| 产品应用 | IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 104kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MLK2/MAP3K10:421-480/954 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]. Function: Activates the JUN N-terminal pathway (By similarity). Subunit: Homodimer (By similarity). Tissue Specificity: Expressed in brain and skeletal muscle. Post-translational modifications: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation (By similarity). Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain. Contains 1 SH3 domain. SWISS: Q02779 Gene ID: 4294 Database links: Entrez Gene: 4294 Human Entrez Gene: 269881 Mouse Entrez Gene: 308463 Rat Omim: 600137 Human SwissProt: Q02779 Human SwissProt: Q66L42 Mouse Unigene: 466743 Human Unigene: 389883 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |