DUX4 单克隆抗体: ATTO 655
产品名称: DUX4 单克隆抗体: ATTO 655
英文名称: DUX4 Monoclonal Antibody: ATTO 655 [P2B1]
产品编号: SMC-192D-A655
产品价格: null
产品产地: 加拿大
品牌商标: StressMarq
更新时间: null
使用范围: WB, IF, IHC
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DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).