TNF monoclonal antibody, clone CH8820
产品名称： TNF monoclonal antibody, clone CH8820
英文名称： TNF monoclonal antibody, clone CH8820
产品编号： MAB6323
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant TNF.
- Immunogen:
- Recombinant protein corresponding to human TNF.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes both, recombinant and native human TNF.
- Form:
- Lyophilized
- Isotype:
- IgG1, kappa
- Storage Buffer:
- Lyophilized from 10 mM PBS, pH 7.0
- Storage Instruction:
- Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing.
- Recommend Usage:
- Sandwich ELISA (Capture Coating Dose: 1.0-2.0 ug/well)
Inhibition Assay (2-5 ng of rTNF-alpha per ug)
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Sandwich ELISA
- Capture Antibody
- Inhibition Assay
- Entrez GeneID:
- 7124
- Gene Name:
- TNF
- Gene Alias:
- DIF,TNF-alpha,TNFA,TNFSF2
- Gene Description:
- tumor necrosis factor (TNF superfamily, member 2)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
- Other Designations:
- APC1 protein,OTTHUMP00000029281,OTTHUMP00000037669,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,cachectin,tumor necrosis factor alpha
- Gene Pathway
- Adipocytokine signaling pathway
- Allograft rejection
- Alzheimer's disease
- Amyotrophic lateral sclerosis (ALS)
- Apoptosis
- Asthma
- Cytokine-cytokine receptor interaction
- Fc epsilon RI signaling pathway
- Graft-versus-host disease
- Hematopoietic cell lineage
- Hypertrophic cardiomyopathy (HCM)
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- Systemic lupus erythematosus
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Toll-like receptor signaling pathway
- Type I diabetes mellitus
- Type II diabetes mellitus
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Abscess
- Absenteeism
- Acne Vulgaris
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Acute Lung Injury
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Adrenal Gland Neoplasms
- Aggressive Periodontitis
- AIDS Dementia Complex
- AIDS-Related Opportunistic Infections
- Albuminuria
- Alcoholism
- alpha 1-Antitrypsin Deficiency
- Alpha-1-antitrypsin deficiency