COX7B2,细胞色素C氧化酶蛋白7B2抗体

产品编号HZ-14015R
英文名称COX7B2
中文名称细胞色素C氧化酶蛋白7B2抗体
别 名COX7B2; CX7B2_HUMAN; Cytochrome c oxidase polypeptide VIIb2; Cytochrome c oxidase subunit 7B2 mitochondrial; Cytochrome c oxidase subunit 7B2, mitochondrial; Cytochrome c oxidase subunit VIIb2; MGC102754.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 新陈代谢 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
COX7B2,细胞色素C氧化酶蛋白7B2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量6.2kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human COX7B2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COX7B2,细胞色素C氧化酶蛋白7B2抗体PubMedPubMed
产品介绍background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subunit:

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the cytochrome c oxidase VIIb family.

Gene ID:
170712

Database links:
Entrez Gene: 170712 Human
Omim: 609811 Human
SwissProt: Q8TF08 Human
Unigene: 479656 Human

COX7B2,细胞色素C氧化酶蛋白7B2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.