重组小鼠白介素-17 Recombinant Murine IL-17

IL4 is a pleiotropic cytokine produced by activated T cells。 IL4 is a ligand for interleukin 4 receptor。 The interleukin 4 receptor also binds to IL13，which may contribute to many overlapping functions of this cytokine and IL13。 STAT6，a signal transducer and activator of transcription，has been shown to play a central role in mediating the immune regulatory signal of this cytokine。 This gene，IL3，IL5，IL13，and CSF2 form a cytokine gene cluster on chromosome 5q，with this gene particularly close to IL13。 IL4，IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome。 Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported。

重组小鼠白介素-17 Recombinant Murine IL-17

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重组小鼠白介素-17 Recombinant Murine IL-17