FITC标记的前列腺素F2a受体抗体PGF2αR
产品名称: FITC标记的前列腺素F2a受体抗体PGF2αR
英文名称: Anti-PTGFR/FITC
产品编号: HZ-10433R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PTGFR/FITC Conjugated antibody
FITC标记的前列腺素F2a受体抗体PGF2αR
英文名称 | Anti-PTGFR/FITC |
中文名称 | FITC标记的前列腺素F2a受体抗体PGF2αR |
别 名 | Prostaglandin F2 alpha Receptor PF2R_HUMAN; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F2-alpha receptor; Prostaglandin receptor 2 alpha; Prostanoid FP receptor; PTGFR; FP; MGC120498; MGC46203. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 神经生物学 细胞膜受体 G蛋白偶联受体 G蛋白信号 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Pig, Cow, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PTGFR |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 5737 Human Omim: 600563 Human SwissProt: P43088 Human Unigene: 654365 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是G蛋白偶联受体家族的成员。该蛋白是前列腺素F2-α(PGF2-α)的受体,已知PGF2-α是一种有效的黄体溶解剂,还可能参与调节眼压和子宫平滑肌收缩。在小鼠中进行敲除研究表明PGF2-α与该受体的相互作用可以启动卵巢黄体细胞的分娩,从而诱导黄体溶解。发现了两个编码不同亚型的转录变体。[ RefSeq,JUL 2008 ]