FES,原癌基因酪氨酸蛋白激酶FES抗体

产品编号HZ-5750R
英文名称FES
中文名称原癌基因酪氨酸蛋白激酶FES抗体
别 名c-fes/fps protein; cFES; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami; Feline sarcoma oncogene; FPS; Oncogene FES; Oncogene FES feline sarcoma virus; Proto oncogene tyrosine protein kinase Fes/Fps; proto-oncogene tyrosine-protein kinase Fes/Fps.
说 明 书0.1ml 0.2ml
研究领域肿瘤 免疫学 信号转导 激酶和磷酸酶
FES,原癌基因酪氨酸蛋白激酶FES抗体抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
FES,原癌基因酪氨酸蛋白激酶FES抗体分 子 量90kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FES
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FES,原癌基因酪氨酸蛋白激酶FES抗体PubMedPubMed
产品介绍background:
FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex.

FES,原癌基因酪氨酸蛋白激酶FES抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.