分子量:12.8 kDa

纯度:>97% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human Thioredoxin-2, His Tag by the LAL method.

Buffer:50 mM Tris, 150 mM NaCl,pH8.0

生物活性:

产品特性:Human Thioredoxin-2, His Tag is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 12.8 kDa. The predicted N-terminus is Met. The reducing (R) protein migrates as 13 kDa in SDS-PAGE .

产品背景:Thioredoxin-2 (TXN2),a member of the thioredoxin family,is also known as mitochondrial (MTRX or Mt-Trx) and TRX2.TXN2 have two important domains: Redox-active center and Transit peptide. TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Also, TXN2 could be involved in the resistance to anti-tumor agents. TNX2 possesses a dithiol-reducing activity as well.