NR4A3 Split FISH Probe
产品名称: NR4A3 Split FISH Probe
英文名称: NR4A3 Split FISH Probe
产品编号: FS0023
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - NR4A3(Texas Red)
Approximately 450kb
Texas Red
9q31.1
- Probe 2:
Size:
Fluorophore:
Location: - NR4A3(FITC)
Approximately 720kb
FITC
9q22.3
- Probe Gap:
- The gap between two probes is approximately 35 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human colon adenocarcinoma (FFPE) stained with NR4A3 Split FISH Probe. Human colon adenocarcinoma showed no NR4A3 gene split.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 8013
- Gene Name:
- NR4A3
- Gene Alias:
- CHN,CSMF,MINOR,NOR1,TEC
- Gene Description:
- nuclear receptor subfamily 4, group A, member 3
- Omim ID:
- 600542
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022775,OTTHUMP00000022776,chondrosarcoma, extraskeletal myxoid, fused to EWS,mitogen induced nuclear orphan receptor,neuron derived orphan receptor,translocated in extraskeletal chondrosarcoma
- Related Disease