Anti-FMO1抗体
产品名称: Anti-FMO1抗体
英文名称: FMO1
产品编号: YB--16152R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
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Anti-FMO1抗体
产品编号 | YB-16152R |
英文名称 | FMO1 |
中文名称 | 肝黄素单加氧酶1抗体 |
别 名 | Dimethylaniline monooxygenase [N oxide forming] 1; Dimethylaniline monooxygenase [N-oxide-forming] 1; Dimethylaniline oxidase 1; Fetal hepatic flavin containing monooxygenase 1; Fetal hepatic flavin-containing monooxygenase 1; Flavin containing monooxygenase 1 (fetal liver); Flavin Containing Monooxygenase 1; FMO 1; FMO1; FMO1_HUMAN; OTTHUMP00000033536; OTTHUMP00000033537. |
规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 60kDa |
细胞定位 | 细胞浆 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FMO1:301-400/532 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Function: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine. Similarity: Belongs to the FMO family. SWISS: Q01740 Gene ID: 2326 Database links: Entrez Gene: 2326 Human Entrez Gene: 14261 Mouse Entrez Gene: 25256 Rat Omim: 136130 Human SwissProt: Q01740 Human SwissProt: P50285 Mouse SwissProt: P36365 Rat Unigene: 1424 Human Unigene: 976 Mouse Unigene: 867 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |