SEMA4G,跨膜蛋白SEMA4G抗体

产品编号HZ-11479R
英文名称SEMA4G
中文名称跨膜蛋白SEMA4G抗体
别 名SEM4G_HUMAN; sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4G; Sema4g; semaphorin 4G; Semaphorin 4G precursor; Semaphorin-4G.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse,
SEMA4G,跨膜蛋白SEMA4G抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量90kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SEMA4G (71-120aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SEMA4G,跨膜蛋白SEMA4G抗体PubMedPubMed
产品介绍background:
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4G (semaphorin-4G) is an 838 amino acid single-pass type I membrane protein that is thought to play a role in axon guidance. Existing as three alternatively spliced isoforms, SEMA4G contains one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single SEMA domain.

Function:
Cell surface receptor for PLXNB2. May play a role in axon guidance.

Subunit:
Interacts with PLXNB2

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the semaphorin family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 PSI domain.
Contains 1 Sema domain.

SEMA4G,跨膜蛋白SEMA4G抗体Database links:
UniProtKB/Swiss-Prot: Q9NTN9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.