ALPL抗体
Applications
| In-house applications |
ELISA, WB, IHC, FC Application not tested? Please see our Guarantee. |
| Published applications |
IHC, WB |
Publications |
9 citations –view here |
| Species specificity |
Human,Mouse,Rat; other species not tested. |
| Published Species |
Mouse, pig, rat |
|
Images
Prev12Next
 HEK-293 cells were subjected to SDS PAGE followed by western blot with 11187-1-AP(ALPL antibody) at dilution of 1:1000 Immunohistochemical of paraffin-embedded human colon cancer using 11187-1-AP(ALPL antibody) at dilution of 1:100 (under 40x lens) Immunohistochemical of paraffin-embedded human colon cancer using 11187-1-AP(ALPL antibody) at dilution of 1:100 (under 10x lens) 1X10^6 HeLa cells were stained with 0.2ug ALPL antibody (11187-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
|
| Positive WB detected in |
HEK-293 cells, HeLa cells, mouse kidney tissue |
| Positive IHC detected in |
Human colon cancer tissue, human liver cancer tissue, human lung cancer tissue |
| Positive FC detected in |
HeLa cells |
| Recommended dilution |
WB : 1:500-1:5000
IHC : 1:20-1:200 |
ALPL抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen |
ALPL fusion protein ag1664 |
Full name |
Alkaline phosphatase, liver/bone/kidney |
Calculated molecular
weight |
57 kDa |
Observed molecular
weight |
80 kDa |
GenBank accession
number |
BC021289 |
Gene ID (NCBI) |
249 |
| Gene symbol |
ALPL |
Synonyms |
Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, ALPL, BLAP, Bone Alkaline Phosphatase, NBAP |
Background ALPL抗体
|
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H (Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol (GPI)(PMID:10839996).This antibody can bind the four mentioned alkaline phosphatases. ALPL抗体
|
XY724Hu22 前列腺素D2合成酶(PGD2S)单克隆抗体 Monoclonal Antibody to Prostaglandin D2 Synthase, Brain (PGD2S) Homo sapiens (Hukl)
XY725Hu22 葡萄糖6磷酸异构酶(GPI)单克隆抗体 Monoclonal Antibody to Glucose 6 Phosphate Isomerase (GPI) Homo sapiens (Hukl)
XY726Hu22 转甲状腺素蛋白(TTR)单克隆抗体 Monoclonal Antibody to Transthyretin (TTR) Homo sapiens (Hukl)
XY728Hu22 环加氧酶1(PTGS1)单克隆抗体 Monoclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1) Homo sapiens (Hukl)
XY729Hu22 桥粒芯糖蛋白1(DSG1)单克隆抗体 Monoclonal Antibody to Desmoglein 1 (DSG1) Homo sapiens (Hukl)
XY730Hu22 骨成型蛋白受体1B(BMPR1B)单克隆抗体 Monoclonal Antibody to Bone Morphogenetic Protein Receptor 1B (BMPR1B) Homo sapiens (Hukl)
XY731Hu22 补体成分7(C7)单克隆抗体 Monoclonal Antibody to Complement Component 7 (C7) Homo sapiens (Hukl)
XY733Hu22 甘露糖受体C2(MRC2)单克隆抗体 Monoclonal Antibody to klnose Receptor C Type 2 (MRC2) Homo sapiens (Hukl)
XY734Hu22 蛋白C(PROC)单克隆抗体 Monoclonal Antibody to Protein C (PROC) Homo sapiens (Hukl)
XY736Hu22 蛋白Z(PROZ)单克隆抗体 Monoclonal Antibody to Protein Z (PROZ) Homo sapiens (Hukl)
XY740Hu22 前列腺素I合酶(PTGIS)单克隆抗体 Monoclonal Antibody to Prostaglandin I Synthase (PTGIS) Homo sapiens (Hukl)
XY741Hu22 Dickkopf相关蛋白1(DKK1)单克隆抗体 Monoclonal Antibody to Dickkopf Related Protein 1 (DKK1) Homo sapiens (Hukl)
XY743Hu22 金属硫蛋白3(MT3)单克隆抗体 Monoclonal Antibody to Metallothionein 3 (MT3) Homo sapiens (Hukl)
XY746Hu22 成纤维细胞生长因子23(FGF23)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 23 (FGF23) Homo sapiens (Hukl)
XY748Hu22 三叶因子2(TFF2)单克隆抗体 Monoclonal Antibody to Trefoil Factor 2 (TFF2) Homo sapiens (Hukl)
XY750Hu22 补体受体2(CR2)单克隆抗体 Monoclonal Antibody to Complement Receptor 2 (CR2) Homo sapiens (Hukl)
