Human Growth Factors & Cytokines
Recombinant Human IL-16 (121 a.a.)





 





		Synonyms :
LCF (Lymphocyte Chemoattractant Factor)



		Description :
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils.  Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer.  However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity.  IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells.  Human and murine IL-16 show significant cross-species reactivity.  Recombinant human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues.



		Catalog #:
200-16A



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability ot chemoattract human CD4+ T-Lymphocytes using a concentration range of 50.0-100.0 ng/ml.



                AA Sequence :
SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S 



		PubMed Link :
IL-16+AND+121


Country of Origin :
USA
















        Size A
2μg
$80 
 


 



        Size B
10μg
$195 
 


 



        Size C
1mg
$5200 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.