ANKRD26,锚蛋白重复结构域蛋白26抗体

产品编号HZ-9755R
英文名称ANKRD26
中文名称锚蛋白重复结构域蛋白26抗体
别 名Ankrd26; Ankyrin repeat domain 26; Ankyrin repeat domain-containing protein 26; Ankyrin repeat domaincontaining protein 26; ANR26_MOUSE.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 干细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,
ANKRD26,锚蛋白重复结构域蛋白26抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量196kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse ANKRD26
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ANKRD26,锚蛋白重复结构域蛋白26抗体PubMedPubMed
产品介绍background:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD26 (ankyrin repeat domain-containing protein 26) is a 1709 amino acid protein that contains five ANK repeats. Expressed at high level in many tissues, including brain, liver, kidney and heart, ANKRD26 may be phosphorylated upon DNA damage by Atm or ATR. ANKRD26 is also expressed in the arcuate and ventromedial nuclei within the hypothalamus and in the ependyma and the circumventricular organs that act as an interface between the peripheral circulation and the brain. It is suggested that alterations in the gene encoding ANKRD26 may lead to obesity. Three isoforms of ANKRD26 exists due to alternative splicing events.

Post-translational modifications:

Similarity:
Contains 5 ANK repeats.

Database links:
Entrez Gene: 232339 Mouse
Entrez Gene: 312667 Rat
SwissProt: Q811D2 Mouse
Unigene: 276116 Mouse

ANKRD26,锚蛋白重复结构域蛋白26抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.