Anti-RASSF6/FITC Conjugated抗体-抗体-抗体-生物在线

Anti-RASSF6/FITC Conjugated抗体

商家询价

产品名称： Anti-RASSF6/FITC Conjugated抗体

英文名称： Anti-RASSF6/FITC

产品编号： YB--5955R-FITC

产品价格： null

产品产地：中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:29:50

使用范围：科研使用

上海钰博生物科技有限公司

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产品详情

Anti-RASSF6/FITC Conjugated抗体

产品编号	YB-5955R-FITC
英文名称	Anti-RASSF6/FITC
中文名称	FITC标记的RAS家族关联结构域蛋白6抗体
别名	Putative RAS binding protein; Ras association domain containing protein 6.RASF6_HUMAN
规格价格	100ul/2980元购买大包装/询价
说明书	100ul
研究领域	肿瘤免疫学信号转导 G蛋白偶联受体
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Rabbit,
产品应用	IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	41kDa
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human RASSF6
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]. Function: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity). Subunit: Interacts with MOAP1 (By similarity). Interaction with activated KRAS is still a matter of debate: interaction has been shown in the mouse (PubMed:17404571), but not in human (PubMed:17367779). Lack of interaction with MRAS, NRAS nor RRAS2 has also been reported (PubMed:17367779). Tissue Specificity: Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. Similarity: Contains 1 Ras-associating domain. Contains 1 SARAH domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.