NLRP1 polyclonal antibody
产品名称： NLRP1 polyclonal antibody
英文名称： NLRP1 polyclonal antibody
产品编号： PAB12885
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NLRP1.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 13 amino acids of human NLRP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- NALP1 antibody is human specific.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- NALPs: a novel protein family involved in inflammation.
Tschopp J, Martinon F, Burns K.Nat Rev Mol Cell Biol. 2003 Feb;4(2):95-104.
- 2.
- A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis.
Chu ZL, Pio F, Xie Z, Welsh K, Krajewska M, Krajewski S, Godzik A, Reed JC.J Biol Chem. 2001 Mar 23;276(12):9239-45. Epub 2000 Dec 11.
- 3.
- Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.
Hlaing T, Guo RF, Dilley KA, Loussia JM, Morrish TA, Shi MM, Vincenz C, Ward PA.J Biol Chem. 2001 Mar 23;276(12):9230-8. Epub 2000 Nov 13.
- Entrez GeneID:
- 22861
- Protein Accession#:
- AAG30288
- Gene Name:
- NLRP1
- Gene Alias:
- CARD7,CLR17.1,DEFCAP,DEFCAP-L/S,DKFZp586O1822,KIAA0926,NAC,NALP1,PP1044,SLEV1,VAMAS1
- Gene Description:
- NLR family, pyrin domain containing 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
- Other Designations:
- NACHT, LRR and PYD containing protein 1,NACHT, leucine rich repeat and PYD (pyrin domain) containing 1,NACHT, leucine rich repeat and PYD containing 1,caspase recruitment domain protein 7,death effector filament-forming Ced-4-like apoptosis protein,nucleo