FITC标记的锌指蛋白BED3抗体
产品名称： FITC标记的锌指蛋白BED3抗体
英文名称： Anti-ZBED3/FITC
产品编号： HZ-13553R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZBED3/FITC Conjugated antibody
FITC标记的锌指蛋白BED3抗体
| 英文名称 | Anti-ZBED3/FITC |
| 中文名称 | FITC标记的锌指蛋白BED3抗体 |
| 别 名 | MGC15435; ZBED3; ZBED3_HUMAN; Zinc finger BED domain containing 3; Zinc finger BED domain-containing protein 3; Zinc finger BED type containing 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 干细胞 锌指蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZBED3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression. Subunit: Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations. Subcellular Location: Cytoplasm. Membrane. Note=Colocalizes with AXIN1 in the cytoplasm. Similarity: Contains 1 BED-type zinc finger. Database links: Entrez Gene: 84327 Human Entrez Gene: 72114 Mouse Entrez Gene: 361881 Rat SwissProt: Q96IU2 Human Unigene: 584988 Human Unigene: 3774 Mouse Unigene: 103511 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
通过稳定细胞质β-连环素，在激活正常Wnt/β-连环素信号通路中起正调节作用。参与转录激活Wnt靶基因表达。