Recombinant Mouse Interleukin-1 alpha (Mouse IL-1α)
产品名称： Recombinant Mouse Interleukin-1 alpha (Mouse IL-1α)
英文名称： Recombinant Mouse Interleukin-1 alpha (Mouse IL-1α)
产品编号： 90139ES10
产品价格： 535.00
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2024-04-26T14:28:11
使用范围： null
| 规格 | 价格 |
| 2 μg | 535.0 |
| 10 μg | 1855.0 |
| 50 μg | 3855.0 |
| 100 μg | 5785.0 |
| 500 μg | 15775.0 |
- 联系人 : 李自转
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Product Information
Product Name
Cat#
Size
Recombinant Mouse IL-1α Protein
90139ES05
2 μg
90139ES10
10 μg
90139ES50
50 μg
90139ES60
100 μg
90139ES76
500 μg
Product Description
Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1,and is a cytokine of the interleukin-1 family. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. IL-1 is a major immunoregulatory/proinflammatory cytokine which also affects fibroblast proliferation and function and therefore it was of interest to investigate whether its constitutive expression influences the in vivo tumorigenic potential of transformed fibroblastoid cell lines.
Product Properties
Synonyms
Interleukin-1 alpha, IL-1α, BAF, IL-1F1, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha
Accession
Q3U0Y6
GeneID
16175
Source
E.coli-derived mouse IL-1alpha protein, Ser115-Ala270.
Molecular Weight
Approximately 17.9 kDa.
AA Sequence
SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 97% by SDS-PAGE and HPLC analyses.
Biological Activity
The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/mL, corresponding to a specific activity of > 5.0 × 108 IU/mg. Fully biologically active when compared to standard.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
- Avoid repeated freeze-thaw cycles.
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only!
HB240321
.HB220210