ICAM1 monoclonal antibody, clone 1H4 (APC)
产品名称： ICAM1 monoclonal antibody, clone 1H4 (APC)
英文名称： ICAM1 monoclonal antibody, clone 1H4 (APC)
产品编号： MAB5085
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ICAM1.
- Immunogen:
- Native purified ICAM1 from Raji cells and spleen cells fused with NS1 cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 85-110
- Reactivity:
- Human
- Specificity:
- This antibody reacts with CD54 (ICAM-1), a 85-110 KDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells; the expression of CD54 is upregulated by activation.
- Form:
- Liquid
- Conjugation:
- APC
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites.
Williams DT, Chaudhry Y, Goodfellow IG, Lea S, Evans DJ.J Gen Virol. 2004 Mar;85(Pt 3):731-8.
- 2.
- Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus.
Ockenhouse CF, Betageri R, Springer TA, Staunton DE.Cell. 1992 Jan 10;68(1):63-9.
- 3.
- Adhesion receptors of the immune system.
Springer TA.Nature. 1990 Aug 2;346(6283):425-34.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 3383
- Gene Name:
- ICAM1
- Gene Alias:
- BB2,CD54,P3.58
- Gene Description:
- intercellular adhesion molecule 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq
- Other Designations:
- cell surface glycoprotein P3.58,human rhinovirus receptor,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- Interactome
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- Acute Disease
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