Anti-BDNF Polyclonal Antibody
产品名称: Anti-BDNF Polyclonal Antibody
英文名称: ANON2;BULN2
产品编号: K008206P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IHC
北京索莱宝科技有限公司--实验室产品
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BDNF is a member of the family of neurotrophic factors. It was first explored and purified from pig brain in 1982, and other members of the neurotrophin family were successively discovered. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It also plays a role in the regulation of stress response and in the biology of mood disorders. The BDNF gene is rather complex in its structure and it can express four different mRNA isoforms by alternative splicing, producing 28-37 kDa proteins.