NXPH2,神经外营养蛋白2抗体

产品编号HZ-11171R
英文名称NXPH2
中文名称神经外营养蛋白2抗体
别 名Neurexophilin2; Neurexophilin 2; Neurexophilin-2; NPH2; Nxph2; Nxph-2; NXPH2_HUMAN; MGC125479; MGC125477; MGC125478; MGC125480.
说 明 书0.1ml 0.2ml
研究领域神经生物学 信号转导 细胞粘附分子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
NXPH2,神经外营养蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NXPH2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
NXPH2,神经外营养蛋白2抗体PubMedPubMed
产品介绍background:
Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I?(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.

Function:
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.

Subunit:
Belongs to the neurexophilin family.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in brain and kidney.

Post-translational modifications:
May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells (By similarity).

Similarity:
Belongs to the neurexophilin family.

Database links:
UniProtKB/Swiss-Prot: O95156.2

NXPH2,神经外营养蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.