Anti-Cullin 1/FITC Conjugated抗体
产品名称： Anti-Cullin 1/FITC Conjugated抗体
英文名称： Anti-Cullin 1/FITC
产品编号： YB--4208R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-Cullin 1/FITC Conjugated抗体
| 产品编号 | YB-4208R-FITC |
| 英文名称 | Anti-Cullin 1/FITC |
| 中文名称 | FITC标记的Cullin1抗体 |
| 别 名 | Cullin-1; CUL 1; CUL1; Cullin1; MGC149834; MGC149835. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 信号转导 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 85kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cullin 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast. Tissue Specificity: Expressed in lung fibroblasts. Post-translational modifications: Neddylated; which enhances the ubiquitination activity of SCF. Deneddylated via its interaction with the COP9 signalosome (CSN) complex. Deneddylated by Epstein-Barr virus BPLF1 leading to a S-phase-like environment that is required for efficient replication of the viral genome. Similarity: Belongs to the cullin family. Database links: Entrez Gene: 8454 Human Entrez Gene: 26965 Mouse Entrez Gene: 362356 Rat Omim: 603134 Human SwissProt: Q13616 Human SwissProt: Q9WTX6 Mouse Unigene: 146806 Human Unigene: 87611 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |