ASAH2-Specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ASAH2-Specific抗体

ASAH2-Specific抗体

商家询价

产品名称： ASAH2-Specific抗体

英文名称： ASAH2-SpecificAntibody

产品编号： XY19513-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ASAH2-SPECIFIC抗体

Applications
Tested Applications: ELISA
Specificity Reaction: Human, mouse, rat; Other species are not tested.Please decide the specificity by homology
Recommended dilution  
 ASAH2-SPECIFIC抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
Caculated Molecular
Weight:		 86 kDa Observed Molecular 
Weight:		  
GenbankNo NM_019893 GeneID: 56624
Symbol ASAH2 Synonyms ASAH2, NCDase, HNAC1, Acylsphingosine deacylase 2, hCD
Background ASAH2-SPECIFIC抗体

ASAH2, also named as HNAC1, belongs to the neutral ceramidase family. ASAH2 catalyze the reaction: N-acylsphingosine + H2O = a carboxylate + sphingosine. ASAH2 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. ASAH2 acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. And ASAH2 acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. ASAH2 is probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract. ASAH2-SPECIFIC抗体

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