OPRS1 Pre-design Chimera RNAi
产品名称： OPRS1 Pre-design Chimera RNAi
英文名称： OPRS1 Pre-design Chimera RNAi
产品编号： H00010280-R07
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_147157
- Target Region:
- 3' Untranslated Region (3'UTR)
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 10280
- Gene Name:
- SIGMAR1
- Gene Alias:
- FLJ25585,MGC3851,OPRS1,SR-BP1
- Gene Description:
- sigma non-opioid intracellular receptor 1
- Omim ID:
- 601978
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000000515,OTTHUMP00000000516,OTTHUMP00000000517,OTTHUMP00000021286,SR31747 binding protein 1,aging-associated gene 8 protein,opioid receptor, sigma 1,sigma1 receptor,type I sigma receptor
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Bulimia
- Cerebral Amyloid Angiopathy
- Cognition
- Cognition Disorders
- Depressive Disorder, Major
- Genetic Predisposition to Disease
- Neuroblastoma
- Neuropsychological Tests
- Personality Disorders
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenia
- Schizophrenia, Disorganized
- Schizophrenia, Paranoid