ARHGAP10抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ARHGAP10抗体

ARHGAP10抗体

商家询价

产品名称： ARHGAP10抗体

英文名称： ARHGAP10Antibody

产品编号： XY55139-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ARHGAP10抗体

Applications
Tested Applications: ELISA, WB, IHC
Cited applications WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Cited species Mouse
Positive WB detected in Human heart tissue, HEK-293 cells, mouse kidney tissue
Positive IHC detected in Human skeletal muscle tissue, human heart tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 ARHGAP10抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 55139-1-AP;human heart tissuehuman heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP(ARHGAP10 antibody) at dilution of 1:800
  • 55139-1-AP;human skeletal muscleImmunohistochemical of paraffin-embedded human skeletal muscle using 55139-1-AP(ARHGAP10 antibody) at dilution of 1:50 (under 10x lens)
  • 55139-1-AP;human skeletal muscleImmunohistochemical of paraffin-embedded human skeletal muscle using 55139-1-AP(ARHGAP10 antibody) at dilution of 1:50 (under 40x lens)
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information ARHGAP10抗体
Immunogen: Peptide Full Name: Rho GTPase activating protein 10
Caculated Molecular
Weight:		 89 kDa Observed Molecular 
Weight:		 89 kDa
GenbankNo NM_024605 GeneID: 79658
Symbol ARHGAP10 Synonyms ARHGAP10, FLJ20896, FLJ41791, Graf related protein 2, GRAF2, PS GAP, PSGAP
Background

ARHGAP10, also named as GRAF2, is GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. It is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. ARHGAP10 inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. It stabilizes PAK-2p34 thereby increasing stimulation of cell death. The antibody is specific to ARHGAP10. ARHGAP10抗体

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