Iterative Crystallography Service：Mitotic arrest deficient 2
产品名称： Iterative Crystallography Service：Mitotic arrest deficient 2
英文名称： Iterative Crystallography Service：Mitotic arrest deficient 2
产品编号：
产品价格： 询价
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http://www.creative-biostructure.com/Iterative-crystallography/Iterative-crystallography-CBCRY02.htm
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Cat. No. |
CBCRY02 |
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Background |
MAD2 (mitotic arrest deficient 2) is one of the kinetochore protein present on the chromosome during cell division. It is involved in making sure all chromosomes are attached to the mitotic spindle before the beginning of anaphase. |
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Molecular description |
Protein Classification |
Cell Cycle |
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Structure Weight |
288687.00 Da |
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Polymer |
1 |
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Molecule |
Mitotic Spindle assembly checkpoint protein MAD2A |
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Chain Length |
206 amino acids |
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Crystal Description |
PDB ID |
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MMDB ID |
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Source |
E.coli |
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Method |
X-Ray Diffraction |
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Resolution |
1.95 Å |
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Ligand Chemical Component |
Chloride ion, Magnesium ion, PE3, PE4, PEG |
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Gene information |
Gene Name |
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Synonyms |
HSMAD2; MAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like 1; MAD2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1 |
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UniProt ID |
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GeneID |
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Chromosome Location |
4q27 |
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Function |
protein binding |
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Reference |
Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X. (2008) Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol. 6: E50 |
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