ENDOGL1,核酸内切酶G样蛋白1抗体

产品编号HZ-14592R
英文名称ENDOGL1
中文名称核酸内切酶G样蛋白1抗体
别 名Endo G like 1; Endo G-like 1; ENDOGL 1; ENDOGL2; Endonuclease G like 1; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; EXOG; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 新陈代谢 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken,
ENDOGL1,核酸内切酶G样蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量41kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ENDOGL1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ENDOGL1,核酸内切酶G样蛋白1抗体PubMedPubMed
产品介绍background:
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]

Function:
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity.

Subcellular Location:
Mitochondrion inner membrane.

Tissue Specificity:
Ubiquitous.

ENDOGL1,核酸内切酶G样蛋白1抗体Similarity:
Belongs to the DNA/RNA non-specific endonuclease family.

Gene ID:
9941

Database links:
Entrez Gene: 9941 Human
Entrez Gene: 208194 Mouse
Entrez Gene: 301062 Rat
Omim: 604051 Human
SwissProt: Q9Y2C4 Human
SwissProt: Q8C163 Mouse
Unigene: 517897 Human
Unigene: 101578 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.