Blood Group Antigen Precursor,血型抗原前体蛋白抗体

产品编号HZ-7589R
英文名称Blood Group Antigen Precursor
中文名称血型抗原前体蛋白抗体
别 名A transferase; Abo; ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase); ABO glycosyltransferase; B (A) alpha 1, 3 glactosyltransferase; B transferase; BGAT_HUMAN; Fucosylglycoprotein 3 alpha galactosyltransferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha N acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein fucosylgalactoside alpha galactosyltransferase; Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; GTB; Histo blood group A transferase; Histo blood group A2 transferase; Histo blood group ABO system transferase; Histo blood group B transferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT.
说 明 书0.1ml 0.2ml
Blood Group Antigen Precursor,血型抗原前体蛋白抗体研究领域心血管 细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Chimpanzee,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量41kDa
细胞定位细胞浆 细胞膜 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Blood Group Antigen Precursor
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Blood Group Antigen Precursor,血型抗原前体蛋白抗体PubMedPubMed
产品介绍background:
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Function:
This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

Blood Group Antigen Precursor,血型抗原前体蛋白抗体Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 6 family.

Gene ID:
28

Database links:
Entrez Gene: 28 Human
Entrez Gene: 80908 Mouse
Entrez Gene: 65270 Rat
Omim: 110300 Human
SwissProt: P16442 Human
SwissProt: P38649 Mouse
SwissProt: Q9ET32 Rat
Unigene: 654423 Human
Unigene: 160386 Mouse
Unigene: 112591 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.